Healing Properties of Some Indian Medicinal Plants against Indomethacin-Induced Gastric Ulceration of Rats
نویسندگان
چکیده
The healing activity of the ethanol extracts of Piper betel, Emblica officinalis, Terminalia bellerica, and Terminalia chebula against the indomethacin-induced stomach ulceration has been studied and compared with that of misoprostol. Compared to autohealing, all the drugs accelerated the healing process, albeit to different extents. The relative healing activities of the extracts was P. betel>E. officinalis>T. bellerica~T. chebula, that correlated well with their in vivo antioxidant and mucin augmenting activities. The excellent healing activity of the extracts of P. betel and E. officinalis indicated a major role of mucin protection and regeneration in the healing of nonsteroidal anti-inflammatory drugs mediated stomach ulceration.
منابع مشابه
Protective Effects of Vaccinium arctostaphylos L., Berberis thunbergii var. atropurpurea Chenault, Elaeagnus angustifolia L. and Launaea acanthodes (Boiss.) O. Kuntze against Indomethacin-Induced Gastric Ulcers in Rats
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ورودعنوان ژورنال:
- Journal of Clinical Biochemistry and Nutrition
دوره 41 شماره
صفحات -
تاریخ انتشار 2007